
These may be the last days of Amazon’s Mechanical Turk.
Will Amazon fully shut down Mechanical Turk for all users by October 1, 2026?
Resolves by Oct 1, 2026
Amazon's crowdsourcing service, which launched in 2005 as a marketplace where workers completed simple automated tasks for small payments, will stop accepting new customers as of July 30, 2026, though existing customers can continue using it. The service became notable in debates about crowdsourced labor ethics and later became integrated into AI development, where companies used it to annotate data for training neural networks. The decision to close to new customers signals the service is declining, as it will no longer receive new features despite Amazon maintaining security improvements. The platform's relevance has been complicated by the emergence of large language models, with a 2023 analysis finding that between 33 and 46 percent of workers were using these models to complete their tasks, raising questions about data reliability.

In this tutorial, we build an end-to-end autonomous AI co-scientist workflow for next-generation EGFR inhibitor discovery, focusing on the C797S osimertinib-resistance mutation in non-small cell lung cancer. We start by resolving the biological target through ChEMBL and UniProt, then mine curated EGFR IC50 bioactivity records and convert them into a clean pIC50 modeling dataset. We use RDKit to standardize molecules, remove salts, aggregate replicate measurements, compute Morgan fingerprints, e

The update is part of Apple's broader effort to make Siri feel more natural and personal, as it rebuilds the assistant around generative AI.

In the AI era, platforms have no choice but to fight fire with fire to cull spam.
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